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Symbol
Name
ID
Lipe
lipase, hormone sensitive
MGI:96790
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Abnormal circulating lipid concentration
Hyperlipidemia
Hypertriglyceridemia
Elevated serum creatine kinase
Diabetes mellitus
Insulin-resistant diabetes mellitus
Insulin resistance
Decreased adiponectin level
Decreased serum leptin
Disease(s) Associated with LIPE
familial partial lipodystrophy type 6

Mouse Phenotypes
abnormal insulin secretion
decreased susceptibility to diet-induced obesity
increased circulating glucose level
hyperglycemia
decreased circulating insulin level
increased circulating insulin level
decreased circulating leptin level
increased circulating leptin level
abnormal circulating cholesterol level
increased circulating cholesterol level
abnormal circulating free fatty acids level
decreased circulating free fatty acid level
increased circulating free fatty acid level
decreased circulating glycerol level
decreased circulating triglyceride level
increased circulating triglyceride level
increased oxygen consumption
abnormal glucose homeostasis
impaired glucose tolerance
decreased glycogen level
abnormal hepatic glucose production
insulin resistance
decreased circulating adiponectin level
abnormal lipid homeostasis
abnormal cholesterol homeostasis
abnormal lipid level
abnormal fatty acid level
abnormal triglyceride level
decreased liver triglyceride level
decreased triglyceride level
increased triglyceride level
abnormal lipolysis
abnormal metabolism
abnormal enzyme/coenzyme activity
Availability Mouse Genotype
Lipetm1Gam/Lipetm1Gam
Lipetm1Ishi/Lipetm1Ishi
Lipetm1Land/Lipetm1Land
Lipetm1Rze/Lipetm1Rze
Lipetm2Rze/Lipetm2Rze
Tg(Ins2-cre)25Mgn/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory