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Symbol
Name
ID
Lcat
lecithin cholesterol acyltransferase
MGI:96755
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased HDL cholesterol concentration
Hypertriglyceridemia
Proteinuria
Disease(s) Associated with LCAT
Norum disease

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased circulating HDL cholesterol level
increased circulating HDL cholesterol level
decreased circulating VLDL cholesterol level
decreased circulating cholesterol level
increased circulating cholesterol level
abnormal circulating phospholipid level
increased circulating phospholipid level
increased circulating triglyceride level
abnormal circulating protein level
abnormal lipid homeostasis
abnormal cholesterol homeostasis
decreased cholesterol level
increased cholesterol level
abnormal lipid level
increased urine protein level
Availability Mouse Genotype
Lcattm1Hgc/Lcattm1Hgc
Lcattm1Nsa/Lcattm1Nsa *
Tg(Lcat)1Ssf/Tg(Lcat)1Ssf
Lcattm1Hgc/Lcat+
Lcattm1Nsa/Lcat+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory