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Symbol
Name
ID
Krt14
keratin 14
MGI:96688
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Atypical scarring of skin
Atrophic scars
Oral mucosal blisters
Palmoplantar blistering
Palmoplantar hyperkeratosis
Recurrent skin infections
Abnormality of the nail
Abnormal fingernail morphology
Dystrophic fingernails
Dystrophic toenail
Aplasia/Hypoplasia of the nails
Nail dysplasia
Ridged nail
Nail dystrophy
Onychogryposis
Abnormal blistering of the skin
Abnormality of skin pigmentation
Hyperpigmentation of the skin
Hypopigmentation of the skin
Milia
Skin ulcer
Skin vesicle
Hyperkeratosis
Palmoplantar keratoderma
Squamous cell carcinoma of the skin
Disease(s) Associated with KRT14
epidermolysis bullosa simplex
epidermolysis bullosa simplex Dowling-Meara type
epidermolysis bullosa simplex generalized type
epidermolysis bullosa simplex localized type

Mouse Phenotypes
abnormal keratinocyte apoptosis
abnormal epidermal layer morphology
abnormal epidermis stratum basale morphology
abnormal epidermis stratum corneum morphology
abnormal keratinocyte morphology
blistering
increased skin papilloma incidence
Availability Mouse Genotype
Krt14tm1(Krt10)Pko/Krt14tm1(Krt10)Pko
Krt14tm1Der/Krt14tm1Der
Krt14tm1Efu/Krt14tm1Efu
Krt14tm2Der/Krt14+
Krt14tm1Der/Krt14+
Tg(KRT14-cre/PGR)1Der/?  (conditional)
Krt14tm1Der/Krt14+
Tg(KRT5-cre/PGR)1Der/?  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory