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Symbol
Name
ID
Jak2
Janus kinase 2
MGI:96629
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Fever
Increased level of L-fucose in urine
Disease(s) Associated with JAK2
myelofibrosis
stomach cancer

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased circulating luteinizing hormone level
decreased circulating iron level
abnormal blood coagulation
abnormal thrombosis
abnormal protein level
abnormal cytokine level
abnormal enzyme/coenzyme activity
Availability Mouse Genotype
Jak2tm1.1Jlvl/Jak2tm1.1Jlvl
Jak2tm1Kf/Jak2+
Jak2tm1Kuw/Jak2tm1Kuw
Tg(Gnrh1-cre)35Awo/0  (conditional)
*
Jak2tm1.1Ble/Jak2+
Commd10Tg(Vav1-icre)A2Kio/Commd10+  (conditional)
Jak2tm1(JAK2)Argr/Jak2+
Dppa3tm1(cre)Peli/Dppa3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory