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Symbol
Name
ID
Itga2
integrin alpha 2
MGI:96600
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgE level
Type II diabetes mellitus
Insulin resistance
Macroscopic hematuria
Decreased level of D-mannose in urine
Disease(s) Associated with ITGA2
Behcet's disease
Glanzmann's thrombasthenia
thrombocytopenia
type 2 diabetes mellitus

Mouse Phenotypes
homeostasis/metabolism phenotype
abnormal platelet physiology
abnormal platelet aggregation
decreased platelet aggregation
Availability Mouse Genotype
Itga2tm1.1Eck/Itga2tm1.1Eck *
Itga2tm1Ztr/Itga2tm1Ztr
Itga2tm1.1Eck/Itga2+
Itga2tm1.1Tkun/Itga2tm1.1Tkun
Tg(Pf4-icre)Q3Rsko/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory