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Symbol
Name
ID
Irf1
interferon regulatory factor 1
MGI:96590
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
hematopoietic system phenotype
abnormal T cell proliferation
abnormal thymus cell ratio
increased double-positive T cell number
increased B-1 B cell number
decreased NK cell number
abnormal T cell number
increased T-helper 2 cell number
increased CD4-positive, alpha beta T cell number
decreased CD8-positive, alpha-beta T cell number
abnormal T cell morphology
abnormal splenocyte morphology
abnormal lymphocyte physiology
abnormal immunoglobulin level
impaired natural killer cell mediated cytotoxicity
abnormal macrophage physiology
Availability Mouse Genotype
Irf1M1Btlr/Irf1M1Btlr *
Irf1m2Btlr/Irf1m2Btlr
Irf1M3Btlr/Irf1M3Btlr
Irf1tm1Cwe/Irf1tm1Cwe
Irf1tm1Mak/Irf1tm1Mak
Irf1M1Btlr/Irf1+ *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory