Symbol
Name
ID

Il2ra
interleukin 2 receptor, alpha chain
MGI:96549

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Decreased lymphocyte proliferation in response to anti-CD3	Decreased circulating IgA level	Increased circulating IgE level	Decreased specific anti-polysaccharide antibody level	Decreased level of 1,5 anhydroglucitol in serum	Hyperglycemia	Diabetes mellitus	Type I diabetes mellitus	Ketoacidosis
Disease(s) Associated with IL2RA	Decreased lymphocyte proliferation in response to anti-CD3	Decreased circulating IgA level	Increased circulating IgE level	Decreased specific anti-polysaccharide antibody level	Decreased level of 1,5 anhydroglucitol in serum	Hyperglycemia	Diabetes mellitus	Type I diabetes mellitus	Ketoacidosis
immunodeficiency 41
type 1 diabetes mellitus
type 1 diabetes mellitus 10

Mouse Phenotypes

decreased salivation

decreased blood urea nitrogen level

decreased circulating glucose level

decreased circulating HDL cholesterol level

decreased circulating cholesterol level

decreased circulating calcium level

increased circulating phosphate level

decreased circulating alkaline phosphatase level

increased circulating aspartate transaminase level

decreased circulating serum albumin level

decreased circulating total protein level

improved glucose tolerance

abnormal cholesterol homeostasis

Availability

Mouse Genotype

Il2ra^{tm1b(EUCOMM)Wtsi}/Il2ra^{tm1b(EUCOMM)Wtsi}

Il2ra^tm1Dw/Il2ra^tm1Dw

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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