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Symbol
Name
ID
Il1b
interleukin 1 beta
MGI:96543
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgE level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Abnormality of chromosome stability
Chromosome breakage
Hypercalcemia
Decreased level of 1,5 anhydroglucitol in serum
Elevated circulating creatinine concentration
Hyperproteinemia
Elevated circulating hepatic transaminase concentration
Hyperglycemia
Diabetes mellitus
Type II diabetes mellitus
Insulin resistance
Elevated sweat chloride
Ketoacidosis
Dehydration
Pleural effusion
Fever
Abnormality of vitamin B12 metabolism
Hepatic steatosis
Hypercalciuria
Hematuria
Pyuria
Increased level of L-fucose in urine
Proteinuria
Amyloidosis
Increased circulating free T3
Increased circulating free T4 concentration
Decreased thyroid-stimulating hormone level
Disease(s) Associated with IL1B
cystic fibrosis
Graves' disease
IgA glomerulonephritis
metabolic dysfunction-associated steatotic liver disease
multiple myeloma
pancreatic cancer
stomach cancer
systemic lupus erythematosus
systemic scleroderma
thrombocytopenia
type 1 diabetes mellitus
type 2 diabetes mellitus

Mouse Phenotypes
abnormal vascular wound healing
decreased circulating corticosterone level
decreased circulating interleukin-1 beta level
impaired febrile response
abnormal insulin-like growth factor I level
decreased susceptibility to injury
Availability Mouse Genotype
Il1btm1Dch/Il1btm1Dch
Il1btm1Lvp/Il1btm1Lvp
Il1btm1Yiw/Il1btm1Yiw

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory