About   Help   FAQ
Symbol
Name
ID
Il10ra
interleukin 10 receptor, alpha
MGI:96538
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Colitis
Enterocolitis
Perianal abscess
Crohn's disease
Folliculitis
Pyoderma
Disease(s) Associated with IL10RA
inflammatory bowel disease 28

Mouse Phenotypes
immune system phenotype
decreased splenocyte proliferation
increased susceptibility to induced colitis
cecum inflammation
colitis
increased neutrophil cell number
abnormal lymphocyte cell number
abnormal regulatory T cell number
decreased T cell number
decreased lymphocyte cell number
increased IgG level
increased circulating interferon-gamma level
increased circulating interleukin-1 alpha level
increased circulating interleukin-1 beta level
increased circulating interleukin-12 level
increased circulating interleukin-17 level
increased circulating interleukin-2 level
increased circulating interleukin-6 level
increased circulating tumor necrosis factor level
abnormal cytokine level
abnormal chemokine level
autoimmune response
increased anti-chromatin antibody level
increased susceptibility to parasitic infection
Availability Mouse Genotype
Il10ram1Jskg/Il10ram1Jskg
Il10ratm1.2Jack/Il10ratm1.2Jack
Il10ratm1b(KOMP)Wtsi/Il10ratm1b(KOMP)Wtsi
Il10raNZW/Il10ra+
Il10ratm1.1Jack/Il10ratm1.1Jack
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Il10ratm1.1Jack/Il10ratm1.1Jack
Tg(Cd4-cre)1Cwi/0  (conditional)
*
Cd19tm1(cre)Cgn/Cd19+
Il10ratm1.1Jack/Il10ratm1.1Jack  (conditional)
*
Il10ratm1.1Tlg/Il10ratm1.1Tlg
Tg(Cd4-cre)1Cwi/?  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/23/2021
MGI 6.16
The Jackson Laboratory