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Symbol
Name
ID
Il10
interleukin 10
MGI:96537
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Abnormality of blood and blood-forming tissues
Disease(s) Associated with IL10
rheumatoid arthritis

Mouse Phenotypes
decreased T cell proliferation
increased thymus weight
thymus hyperplasia
abnormal myelopoiesis
anemia
hypochromic anemia
microcytic anemia
absent erythroid progenitor cell
decreased erythrocyte cell number
decreased hemoglobin content
increased granulocyte number
increased myeloid dendritic cell number
abnormal lymphocyte cell number
increased plasma cell number
increased B cell number
increased CD4-positive, alpha beta T cell number
increased T cell number
abnormal leukocyte morphology
abnormal myeloid leukocyte morphology
decreased spleen iron level
decreased spleen red pulp amount
spleen hyperplasia
increased IgE level
increased IgG1 level
increased IgG2a level
abnormal CD8-positive, alpha-beta T cell physiology
abnormal regulatory T cell physiology
Availability Mouse Genotype
Il10tm1.1Roer/Il10tm1.1Roer
Il10tm1Cgn/Il10tm1Cgn
Il10tm1Roer/Il10tm1Roer
Foxp3tm4(YFP/icre)Ayr/Y  (conditional)
Cd19tm1(cre)Cgn/Cd19+
Il10tm1Roer/Il10tm1Roer  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory