Symbol
Name
ID

Igf1r
insulin-like growth factor I receptor
MGI:96433

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes	Bone pain	Pathologic fracture	Back pain	Osteoporosis
Disease(s) Associated with IGF1R	Bone pain	Pathologic fracture	Back pain	Osteoporosis
neuroblastoma
osteoporosis
pancreatic cancer

Mouse Phenotypes

abnormal osteoblast physiology

abnormal bony labyrinth

thin neurocranium

decreased osteoclast cell number

abnormal osteoclast physiology

abnormal skeleton morphology

decreased trabecular bone volume

decreased osteoblast cell number

abnormal trabecular bone morphology

decreased bone trabecula number

decreased trabecular bone thickness

abnormal skeleton physiology

decreased bone mineralization

decreased bone ossification

delayed bone ossification

Availability

Mouse Genotype

Igf1r^tm1Arge/Igf1r^tm1Arge

Igf1r^tm2.1Arge/Igf1r^tm2.1Arge

Igf1r^tm2Arge/Igf1r^tm2Arge
Tg(BGLAP-cre)1Clem/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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