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Symbol
Name
ID
Htr2c
5-hydroxytryptamine (serotonin) receptor 2C
MGI:96281
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
homeostasis/metabolism phenotype
increased susceptibility to diet-induced obesity
decreased circulating glucose level
increased circulating glucose level
hyperglycemia
increased circulating ghrelin level
increased circulating glucagon level
increased circulating corticosterone level
decreased circulating insulin level
increased circulating insulin level
decreased circulating insulin-like growth factor I level
decreased circulating leptin level
increased circulating leptin level
increased circulating growth hormone level
decreased circulating cholesterol level
decreased circulating triglyceride level
abnormal body temperature
increased energy expenditure
dehydration
decreased oxygen consumption
increased oxygen consumption
abnormal respiratory quotient
impaired glucose tolerance
insulin resistance
abnormal tumor necrosis factor level
abnormal metabolism
increased basal metabolism
abnormal response/metabolism to endogenous compounds
increased sensitivity to xenobiotic induced morbidity/mortality
increased physiological sensitivity to xenobiotic
Availability Mouse Genotype
Htr2ctm2Knk/Htr2ctm2Knk *
Htr2ctm1.1Eme/Y
Htr2ctm1Arte/Y *
Htr2ctm1Jke/Y
Htr2ctm1Jul/Y
Htr2ctm1Knk/Y *
Htr2ctm2Knk/Y *
Htr2ctm2Jke/Htr2ctm2Jke
Tg(Pomc1-cre)16Lowl/0  (conditional)
*
Htr2ctm2Jke/Htr2ctm2Jke
Tg(Pomc-cre/ERT2)#Jke/0  (conditional)
*
Htr2ctm1Jke/Y
Tg(Pomc1-cre)16Lowl/0  (conditional)
*
Htr2ctm2Jke/Y
Tg(Zp3-cre)93Knw/0  (conditional)
Htr2ctm2Jke/Y
Tg(Pomc1-cre)16Lowl/0  (conditional)
*
Htr2ctm2Jke/Y
Tg(Pomc-cre/ERT2)#Jke/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory