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Symbol
Name
ID
Hras
Harvey rat sarcoma virus oncogene
MGI:96224
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Adenoma sebaceum
Redundant neck skin
Deep plantar creases
Deep palmar crease
Alopecia
Generalized hirsutism
Sparse hair
Curly hair
Fragile nails
Concave nail
Deep-set nails
Thin nail
Abnormality of skin pigmentation
Hyperpigmentation of the skin
Irregular hyperpigmentation
Hypopigmentation of the skin
Hypopigmented skin patches
Melanocytic nevus
Congenital giant melanocytic nevus
Nevus
Nevus sebaceous
Linear nevus sebaceous
Nevus spilus
Numerous nevi
Subcutaneous nodule
Acanthosis nigricans
Ichthyosis
Pruritus
Neoplasm of the skin
Basal cell carcinoma
Cutaneous melanoma
Disease(s) Associated with HRAS
Costello syndrome
epidermal nevus
large congenital melanocytic nevus
linear nevus sebaceous syndrome

Mouse Phenotypes
abnormal mammary gland development
abnormal branching of the mammary ductal tree
increased mammary adenocarcinoma incidence
mammary gland hyperplasia
abnormal vibrissa follicle morphology
increased skin papilloma incidence
Availability Mouse Genotype
Hrastm2Xbr/Hrastm2Xbr
Hrastm1Jaf/Hras+
Tg(CAG-cre)13Miya/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory