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Symbol
Name
ID

Hoxa11
homeobox A11
MGI:96172

Phenotype annotations related to skeleton

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Radioulnar synostosis	Limited pronation/supination of forearm
Disease(s) Associated with HOXA11	Radioulnar synostosis	Limited pronation/supination of forearm
radioulnar synostosis

Mouse Phenotypes

skeleton phenotype

abnormal carpal bone morphology

fused carpal bones

abnormal calcaneum morphology

abnormal talus morphology

abnormal radius morphology

short radius

increased diameter of radius

abnormal ulna morphology

short ulna

increased diameter of ulna

abnormal fibula morphology

abnormal tibia morphology

abnormal rib morphology

decreased rib number

thoracic vertebral transformation

increased lumbar vertebrae number

sacral vertebral transformation

Availability

Mouse Genotype

Hoxa11^tm1Mrc/Hoxa11^tm1Mrc

Hoxa11^tm1Ssp/Hoxa11^tm1Ssp

Hoxa11^{tm2.1(Hoxa13)Ssp}/Hoxa11^{tm2.1(Hoxa13)Ssp}

*

Hoxa11^tm1Mrc/Hoxa11⁺

*

Hoxa11^tm1Ssp/Hoxa11⁺

Hoxa11^tm1Ssp/Hoxa11^{tm2.1(Hoxa13)Ssp}

Hoxa11^{tm2.1(Hoxa13)Ssp}/Hoxa11⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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