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Symbol
Name
ID
Hmox1
heme oxygenase 1
MGI:96163
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
increased splenocyte proliferation
increased granulocyte number
abnormal leukocyte cell number
increased B cell number
increased CD4-positive, alpha beta T cell number
increased CD8-positive, alpha-beta T cell number
increased macrophage cell number
enlarged spleen
spleen hyperplasia
abnormal splenic cell ratio
increased circulating tumor necrosis factor level
abnormal lymph node cell ratio
enlarged lymph nodes
decreased interferon-beta secretion
increased interferon-gamma secretion
decreased interleukin-1 beta secretion
decreased interleukin-6 secretion
decreased tumor necrosis factor secretion
increased susceptibility to experimental autoimmune encephalomyelitis
chronic inflammation
decreased inflammatory response
increased inflammatory response
liver inflammation
glomerulonephritis
lung inflammation
decreased susceptibility to bacterial infection induced morbidity/mortality
increased susceptibility to parasitic infection induced morbidity/mortality
increased susceptibility to parasitic infection
decreased susceptibility to viral infection
Availability Mouse Genotype
Hmox1tm1.2Gkl/Hmox1tm1.2Gkl
Hmox1tm1Mlee/Hmox1tm1Mlee
Hmox1tm1Poss/Hmox1tm1Poss
Hmox1tm1.1Gkl/Hmox1tm1.1Gkl
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)
Hmox1tm1.1Hes/Hmox1tm1.1Hes
Lyz2tm1(cre)Ifo/Lyz2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory