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Symbol
Name
ID
Hmgcr
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
MGI:96159
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations

Mouse Phenotypes
increased circulating bilirubin level
hypoglycemia
decreased circulating LDL cholesterol level
increased circulating LDL cholesterol level
decreased circulating cholesterol level
increased circulating cholesterol level
increased circulating free fatty acid level
increased circulating phospholipid level
decreased circulating triglyceride level
abnormal circulating lipoprotein level
abnormal circulating apolipoprotein level
increased circulating alanine transaminase level
increased circulating aspartate transaminase level
decreased liver cholesterol level
increased fatty acid level
increased unsaturated fatty acid level
increased liver triglyceride level
increased collagen level
Availability Mouse Genotype
Hmgcrtm2Ishi/Hmgcrtm2Ishi
Tg(Alb1-cre)1Dlr/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory