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Symbol
Name
ID
Htt
huntingtin
MGI:96067
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Depressivity
Personality changes
Disease(s) Associated with HTT
Huntington's disease

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavior
abnormal learning/memory/conditioning
increased exploration in new environment
increased aggression towards mice
increased grooming behavior
abnormal motor capabilities/coordination/movement
limb grasping
tremors
abnormal motor coordination/balance
enhanced coordination
impaired balance
impaired coordination
impaired limb coordination
abnormal locomotor activation
decreased vertical activity
increased vertical activity
bradykinesia
hyperactivity
hypoactivity
abnormal locomotor coordination
abnormal gait
short stride length
paralysis
hyperresponsive
seizures
tonic-clonic seizures
Availability Mouse Genotype
Htttm1Detl/Htttm1Detl *
Htttm1Mfc/Htttm1Mfc
Htttm2Detl/Htttm2Detl
Htttm2Msl/Htttm2Msl
Htttm3Szi/Htttm3Szi
Htttm4Mem/Htttm4Mem
Htttm5Mem/Htttm5Mem *
Htttm6Mem/Htttm6Mem
Htttm1.1Pfs/Htt+
Htttm1Detl/Htt+ *
Htttm1Hay/Htt+
Htttm1Mem/Htttm6Mem
Htttm2.1Pfs/Htt+
Htttm2Detl/Htt+
Htttm3Szi/Htt+
Htttm6Mem/Htttm8Mem
Htttm1Szi/Htttm2Szi
Tg(Camk2a-cre)1Szi/0  (conditional)
Htttm1Szi/Htttm2Szi
Tg(Camk2a-cre)2Szi/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory