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Symbol
Name
ID
Grn
granulin
MGI:95832
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
microgliosis
abnormal macrophage physiology
abnormal microglial cell physiology
abnormal chemokine secretion
increased interleukin-1 beta secretion
increased interleukin-10 secretion
increased interleukin-12 secretion
increased interleukin-6 secretion
increased tumor necrosis factor secretion
kidney inflammation
increased susceptibility to bacterial infection
Availability Mouse Genotype
Grntm1.1Aidi/Grntm1.1Aidi
Grntm1.1Far/Grntm1.1Far
Grntm1.1Geno/Grntm1.1Geno
Grntm1Blrl/Grntm1Blrl
Grntm2.1Far/Grntm2.1Far
Grntm1Far/Grntm1Far
Tg(ITGAM-cre)2781Gkl/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory