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Symbol
Name
ID
Grin2a
glutamate receptor, ionotropic, NMDA2A (epsilon 1)
MGI:95820
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
EEG with centrotemporal focal spike waves
Speech apraxia
Agnosia
Intellectual disability
Aphasia
Dysphasia
Attention deficit hyperactivity disorder
Behavioral abnormality
Delayed speech and language development
Global developmental delay
Seizures
Disease(s) Associated with GRIN2A
Landau-Kleffner syndrome

Mouse Phenotypes
nervous system phenotype
reduced kindling response
abnormal excitatory postsynaptic currents
reduced NMDA-mediated synaptic currents
reduced long term potentiation
abnormal miniature excitatory postsynaptic currents
Availability Mouse Genotype
Grin2atm1.1Jpleo/Grin2atm1.1Jpleo *
Grin2atm1.1Nhk/Grin2atm1.1Nhk *
Grin2atm1.1Ppao/Grin2atm1.1Ppao
Grin2atm1.1Tnkw/Grin2atm1.1Tnkw *
Grin2atm1Mim/Grin2atm1Mim
Grin2atm1Nak/Grin2atm1Nak *
Grin2atm1Rsp/Grin2atm1Rsp *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory