Symbol
Name
ID

Gria4
glutamate receptor, ionotropic, AMPA4 (alpha 4)
MGI:95811

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Negativism
Disease(s) Associated with GRIA4	Negativism
schizophrenia

Mouse Phenotypes

behavior/neurological phenotype

abnormal seizure response to pharmacological agent

abnormal object recognition memory

decreased exploration in new environment

abnormal spatial reference memory

abnormal spatial working memory

enhanced spatial working memory

increased anxiety-related response

decreased startle reflex

decreased grip strength

decreased vertical activity

increased vertical activity

increased locomotor activity

induced hyperactivity

increased thermal nociceptive threshold

abnormal social investigation

absence seizures

abnormal spike wave discharge

Availability

Mouse Genotype

Gria4^spkw1/Gria4^spkw1

Gria4^tm1.1Mony/Gria4^tm1.1Mony

Gria4^tm1Dgen/Gria4^tm1Dgen

Gria4^tm1Yfkk/Gria4^tm1Yfkk

Gria4^spkw1/Gria4⁺

Gria4^spkw1/Gria4^tm1Dgen

Gria4^tm1Dgen/Gria4⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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