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Symbol
Name
ID
Gnao1
guanine nucleotide binding protein, alpha O
MGI:95775
Phenotype annotations related to nervous system
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Delayed myelination
Hypoplasia of the corpus callosum
Cerebral atrophy
Hypsarrhythmia
Absent speech
Dystonia
Athetosis
Chorea
Epileptic encephalopathy
Global developmental delay
Generalized tonic seizures
Disease(s) Associated with GNAO1
early infantile epileptic encephalopathy 17

Mouse Phenotypes
abnormal kindling response
increased kindling response
abnormal spike wave discharge
sporadic seizures
abnormal nervous system physiology
abnormal channel response
Availability Mouse Genotype
Gnao1tm1Ejne/Gnao1tm1Ejne
Gnao1tm1Lbi/Gnao1tm1Lbi
Gnao1em1Rneu/Gnao1+
Gnao1tm2.1Rneu/Gnao1+ !
Gnao1tm2Rneu/Gnao1+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/14/2019
MGI 6.14
The Jackson Laboratory