About   Help   FAQ
Symbol
Name
ID
Gata1
GATA binding protein 1
MGI:95661
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormal bleeding
Epistaxis
Joint hemorrhage
Persistent bleeding after trauma
Bruising susceptibility
Petechiae
Anemia of inadequate production
Poikilocytosis
Acanthocytosis
Acute megakaryocytic leukemia
Myeloproliferative disorder
Thrombocytopenia
Congenital thrombocytopenia
Intermittent thrombocytopenia
Decreased mean platelet volume
Disease(s) Associated with GATA1
Down syndrome
thrombocytopenia

Mouse Phenotypes
hematopoietic system phenotype
abnormal megakaryocyte differentiation
abnormal embryonic erythropoiesis
abnormal definitive hematopoiesis
abnormal common myeloid progenitor cell morphology
abnormal erythropoiesis
abnormal myelopoiesis
abnormal thrombopoiesis
extramedullary hematopoiesis
anemia
impaired hematopoiesis
abnormal bone marrow cell morphology/development
decreased bone marrow cell number
abnormal megakaryocyte morphology
increased megakaryocyte cell number
abnormal erythroid progenitor cell morphology
decreased erythroid progenitor cell number
increased erythroid progenitor cell number
abnormal megakaryocyte progenitor cell morphology
decreased eosinophil cell number
abnormal proerythroblast morphology
abnormal erythrocyte morphology
decreased erythrocyte cell number
abnormal hematocrit
decreased hematocrit
anisocytosis
increased number of Howell-Jolly bodies
poikilocytosis
polychromatophilia
increased neutrophil cell number
abnormal platelet morphology
thrombocytopenia
abnormal platelet shape
increased mean platelet volume
abnormal leukocyte cell number
decreased lymphocyte cell number
increased osteoclast cell number
abnormal mononuclear cell morphology
abnormal spleen morphology
abnormal spleen red pulp morphology
decreased spleen red pulp amount
increased spleen weight
enlarged spleen
decreased spleen white pulp amount
increased splenocyte number
pale spleen
abnormal hematopoietic system physiology
Availability Mouse Genotype
Gata1tm1.1Yen/Gata1tm1.1Yen *
Gata1tm1Mym/Gata1tm1Mym
Tg(Gata1)#Mym/0
*
Gata1tm1Sho/Gata1tm1Sho
Tg(Gata1)#Mym/0
*
Gata1tm2.1Sho/Gata1tm2.1Sho
Gata1tm2.1Yen/Gata1tm2.1Yen *
Gata1tm2Sho/Gata1tm2Sho
Gata1tm6Sho/Gata1tm6Sho *
Gata1tm7Sho/Gata1tm7Sho
Gata1tm8.1Sho/Gata1tm8.1Sho
Gata1tm8.2Sho/Gata1tm8.2Sho
Gata1Plt13/Gata1+
Gata1tm1Mym/Gata1+
Gata1tm1Phi/Gata1+
Tg(HBB-Gata1)G4Phi/0
Gata1tm1Sho/Gata1+
Gata1tm2.1Sho/Gata1+
Gata1tm2Sho/Gata1+
Gata1tm5(GATA3)Sho/Gata1+
Gata1Plt13/Y
Gata1tm1Mym/Y
Gata1tm1Mym/Y
Tg(Gata1)#Mym/0
*
Gata1tm1Mym/Y
Tg(Gata1*V205G)1Mym/0
Gata1tm1Sho/Y
Gata1tm1Sho/Y
Tg(Gata1)#Mym/0
*
Gata1tm2.1Sho/Y *
Gata1tm2Sho/Y
Gata1tm4Sho/Y
Gata1tm5(GATA3)Sho/Y
Gata1tm6Sho/Y *
Gata1tm7Sho/Y
Gata1tm8.1Sho/Y
Gata1tm8.2Sho/Y
Gata1tm9Sho/Y *
Gata1tm10Sho/Y *
Tg(HBB-Gata1)G4Phi/Y
Gata1tm1Phi/Gata1+
Tg(HBB-cre)1Phi/0
Tg(HBB-Gata1)G4Phi/0  (conditional)
Gata1tm1Phi/Gata1+
Tg(HBB-cre)1Phi/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/12/2019
MGI 6.14
The Jackson Laboratory