Symbol
Name
ID

Cidec
cell death-inducing DFFA-like effector c
MGI:95585

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Hypertriglyceridemia	Increased C-peptide level	Diabetic ketoacidosis	Insulin-resistant diabetes mellitus	Hepatic steatosis	Decreased adiponectin level	Decreased serum leptin
Disease(s) Associated with CIDEC
familial partial lipodystrophy type 5

Mouse Phenotypes

decreased susceptibility to diet-induced obesity

abnormal adaptive thermogenesis

impaired adaptive thermogenesis

abnormal blood homeostasis

increased fasting circulating glucose level

decreased circulating glucose level

increased circulating insulin level

decreased circulating leptin level

decreased circulating ketone body level

abnormal circulating lipid level

increased circulating cholesterol level

decreased circulating free fatty acids level

increased circulating free fatty acids level

decreased circulating triglyceride level

increased circulating triglyceride level

increased circulating alanine transaminase level

decreased circulating alkaline phosphatase level

increased body temperature

increased energy expenditure

increased oxygen consumption

decreased respiratory quotient

increased respiratory quotient

improved glucose tolerance

increased insulin sensitivity

insulin resistance

enhanced lipolysis

Availability

Mouse Genotype

Cidec^{tm1b(EUCOMM)Wtsi}/Cidec^{tm1b(EUCOMM)Wtsi}

Cidec^tm1Maka/Cidec^tm1Maka

Cidec^tm1Pli/Cidec^tm1Pli

Cidec^tm1.1Gonz/Cidec^tm1.2Gonz
Tg(Fabp4-cre)#Abel/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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