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Symbol
Name
ID
Fn1
fibronectin 1
MGI:95566
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Abnormality of metabolism/homeostasis
Increased urinary type 1 collagen N-terminal telopeptide level
Hyperoxaluria
Abnormal circulating osteocalcin level
Disease(s) Associated with FN1
calcium oxalate nephrolithiasis
membranoproliferative glomerulonephritis
spondylometaphyseal dysplasia corner fracture type

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased susceptibility to induced thrombosis
abnormal protein level
abnormal response to injury
increased susceptibility to ischemic brain injury
increased cerebral infarct size
impaired wound healing
Availability Mouse Genotype
Fn1tm1Feb/Fn1tm1Feb *
Fn1tm2Feb/Fn1tm2Feb
Fn1tm1.1Sakai/Fn1tm1.1Sakai
Tg(Mx1-cre)1Cgn/0  (conditional)
Fn1tm1Ref/Fn1tm1Ref
Tg(Mx1-cre)1Cgn/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory