About   Help   FAQ
Symbol
Name
ID
Fgfr1
fibroblast growth factor receptor 1
MGI:95522
Phenotype annotations related to limbs/digits/tail
Darker colors indicate more annotations
Human Phenotypes
Bowing of the long bones
Clinodactyly of the 5th finger
Postaxial hand polydactyly
Broad distal phalanx of the thumb
Shortening of all middle phalanges of the fingers
Camptodactyly of finger
Short phalanx of finger
Broad thumb
Preaxial hand polydactyly
Symphalangism affecting the phalanges of the hand
Short thumb
Broad proximal phalanx of the hallux
Broad distal phalanx of the hallux
Broad hallux phalanx
Broad hallux
Broad distal hallux
Hallux varus
Preaxial foot polydactyly
Short middle phalanx of toe
Toe syndactyly
2-3 toe syndactyly
Broad phalanx
Clinodactyly
Brachydactyly
Syndactyly
Cutaneous syndactyly
Cutaneous finger syndactyly
Finger syndactyly
Abnormal fibula morphology
Broad first metatarsal
Short first metatarsal
Short metatarsal
Broad metatarsal
Calcaneonavicular fusion
Short foot
Humeroradial synostosis
Short metacarpal
Broad metacarpals
Short palm
Ectrodactyly
Split foot
Broad foot
Synostosis of carpal bones
Broad palm
Elbow ankylosis
Limited elbow movement
Limb undergrowth
Rhizomelia
Rhizomelic arm shortening
Disease(s) Associated with FGFR1
acrocephalosyndactylia
hypogonadotropic hypogonadism 2 with or without anosmia
Jackson-Weiss syndrome
osteoglophonic dysplasia
Pfeiffer syndrome

Mouse Phenotypes
abnormal apical ectodermal ridge morphology
abnormal forelimb bud morphology
absent limb buds
broad limb buds
abnormal limb morphology
abnormal carpal bone morphology
abnormal digit morphology
abnormal phalanx morphology
oligodactyly
forelimb oligodactyly
postaxial polydactyly
syndactyly
abnormal tarsal bone morphology
abnormal forelimb morphology
abnormal forelimb stylopod morphology
abnormal forelimb zeugopod morphology
abnormal hindlimb morphology
short tibia
abnormal embryonic autopod plate morphology
abnormal tail morphology
decreased caudal vertebrae number
abnormal tail development
short tail
Availability Mouse Genotype
Fgfr1tm1Led/Fgfr1tm1Led
Fgfr1tm2.1Cxd/Fgfr1tm2.1Cxd
Fgfr1tm2Jrt/Fgfr1tm2Jrt
Fgfr1tm4.1Sor/Fgfr1tm4.1Sor
Fgfr1tm4Jrt/Fgfr1tm4Jrt
Fgfr1tm5Jrt/Fgfr1tm5Jrt
Fgfr1tm6Jrt/Fgfr1tm6Jrt
Fgfr1tm9.1Sor/Fgfr1tm9.1Sor
Fgfr1tm1Jrt/Fgfr1tm2Jrt
Fgfr1tm1Jrt/Fgfr1tm4Jrt
Fgfr1tm3.2Cxd/Fgfr1tm3.2Cxd
Shhtm1(EGFP/cre)Cjt/Shh+  (conditional)
Fgfr1tm3.2Cxd/Fgfr1tm3.2Cxd
Tg(T-cre)1Lwd/0  (conditional)
Fgfr1tm3.1Cxd/Fgfr1tm3.2Cxd
Shhtm1(EGFP/cre)Cjt/Shh+  (conditional)
Fgfr1tm3.1Cxd/Fgfr1tm3.2Cxd
Tg(T-cre)1Lwd/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory