Symbol Name ID |
Fgfr1
fibroblast growth factor receptor 1 MGI:95522 |
Darker colors indicate more annotations |
Human Phenotypes | Bowing of the long bones |
Clinodactyly of the 5th finger |
Postaxial hand polydactyly |
Broad distal phalanx of the thumb |
Shortening of all middle phalanges of the fingers |
Camptodactyly of finger |
Short phalanx of finger |
Broad thumb |
Preaxial hand polydactyly |
Symphalangism affecting the phalanges of the hand |
Short thumb |
Broad proximal phalanx of the hallux |
Broad distal phalanx of the hallux |
Broad hallux phalanx |
Broad hallux |
Broad distal hallux |
Hallux varus |
Preaxial foot polydactyly |
Short middle phalanx of toe |
Toe syndactyly |
2-3 toe syndactyly |
Broad phalanx |
Clinodactyly |
Brachydactyly |
Syndactyly |
Cutaneous syndactyly |
Cutaneous finger syndactyly |
Finger syndactyly |
Abnormal fibula morphology |
Broad first metatarsal |
Short first metatarsal |
Short metatarsal |
Broad metatarsal |
Calcaneonavicular fusion |
Short foot |
Humeroradial synostosis |
Short metacarpal |
Broad metacarpals |
Short palm |
Ectrodactyly |
Split foot |
Broad foot |
Synostosis of carpal bones |
Broad palm |
Elbow ankylosis |
Limited elbow movement |
Limb undergrowth |
Rhizomelia |
Rhizomelic arm shortening |
Disease(s) Associated with FGFR1 | |||||||||||||||||||||||||||||||||||||||||||||||||
acrocephalosyndactylia | |||||||||||||||||||||||||||||||||||||||||||||||||
hypogonadotropic hypogonadism 2 with or without anosmia | |||||||||||||||||||||||||||||||||||||||||||||||||
Jackson-Weiss syndrome | |||||||||||||||||||||||||||||||||||||||||||||||||
osteoglophonic dysplasia | |||||||||||||||||||||||||||||||||||||||||||||||||
Pfeiffer syndrome |
Mouse Phenotypes | abnormal apical ectodermal ridge morphology |
abnormal forelimb bud morphology |
absent limb buds |
broad limb buds |
abnormal limb morphology |
abnormal carpal bone morphology |
abnormal digit morphology |
abnormal phalanx morphology |
oligodactyly |
forelimb oligodactyly |
postaxial polydactyly |
syndactyly |
abnormal tarsal bone morphology |
abnormal forelimb morphology |
abnormal forelimb stylopod morphology |
abnormal forelimb zeugopod morphology |
abnormal hindlimb morphology |
short tibia |
abnormal embryonic autopod plate morphology |
abnormal tail morphology |
decreased caudal vertebrae number |
abnormal tail development |
short tail |
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Availability | Mouse Genotype | |||||||||||||||||||||||
Fgfr1tm1Led/Fgfr1tm1Led | ||||||||||||||||||||||||
Fgfr1tm2.1Cxd/Fgfr1tm2.1Cxd | ||||||||||||||||||||||||
Fgfr1tm2Jrt/Fgfr1tm2Jrt | ||||||||||||||||||||||||
Fgfr1tm4.1Sor/Fgfr1tm4.1Sor | ||||||||||||||||||||||||
Fgfr1tm4Jrt/Fgfr1tm4Jrt | ||||||||||||||||||||||||
Fgfr1tm5Jrt/Fgfr1tm5Jrt | ||||||||||||||||||||||||
Fgfr1tm6Jrt/Fgfr1tm6Jrt | ||||||||||||||||||||||||
Fgfr1tm9.1Sor/Fgfr1tm9.1Sor | ||||||||||||||||||||||||
Fgfr1tm1Jrt/Fgfr1tm2Jrt | ||||||||||||||||||||||||
Fgfr1tm1Jrt/Fgfr1tm4Jrt | ||||||||||||||||||||||||
Fgfr1tm3.2Cxd/Fgfr1tm3.2Cxd Shhtm1(EGFP/cre)Cjt/Shh+ (conditional) |
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Fgfr1tm3.2Cxd/Fgfr1tm3.2Cxd Tg(T-cre)1Lwd/0 (conditional) |
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Fgfr1tm3.1Cxd/Fgfr1tm3.2Cxd Shhtm1(EGFP/cre)Cjt/Shh+ (conditional) |
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Fgfr1tm3.1Cxd/Fgfr1tm3.2Cxd Tg(T-cre)1Lwd/0 (conditional) |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/19/2024 MGI 6.23 |
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