|
Symbol Name ID |
Fgfr1
fibroblast growth factor receptor 1 MGI:95522 |
| * | Aspects of the system are reported to show a normal phenotype. |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Short neck |
Rhizomelia |
Rhizomelic arm shortening |
Inguinal hernia |
Delayed puberty |
Growth abnormality |
Short stature |
Severe short stature |
Failure to thrive |
Failure to thrive in infancy |
Growth delay |
| Disease(s) Associated with FGFR1 | |||||||||||
| acrocephalosyndactylia | |||||||||||
| hypogonadotropic hypogonadism 2 with or without anosmia | |||||||||||
| osteoglophonic dysplasia | |||||||||||
| Pfeiffer syndrome |
| Mouse Phenotypes | enlarged heart |
long incisors |
abnormal tooth development |
short nasal bone |
abnormal palatal mesenchymal cell proliferation |
abnormal secondary palate development |
failure of palatal shelf elevation |
palatal shelves fail to meet at midline |
persistence of medial edge epithelium during palatal shelf fusion |
decreased palatal shelf size |
facial asymmetry |
midface hypoplasia |
cleft upper lip |
cleft primary palate |
abnormal palatal rugae morphology |
cleft secondary palate |
cleft palate |
complete cleft palate |
abnormal tongue position |
abnormal snout morphology |
short snout |
midline facial cleft |
abnormal outer ear morphology |
abnormal ear position |
lowered ear position |
abnormal ear shape |
excessive cerumen |
small ears |
embryonic growth retardation |
abnormal embryo size |
decreased embryo size |
abnormal head mesenchyme morphology |
growth/size/body region phenotype |
decreased body size |
abnormal embryonic growth/weight/body size |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||
| Fgfr1Hspy/Fgfr1Hspy | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm1.1(KOMP)Vlcg/Fgfr1tm1.1(KOMP)Vlcg | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm1.1Upir/Fgfr1tm1.1Upir | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm1Jrt/Fgfr1tm1Jrt | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm1Led/Fgfr1tm1Led | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm2.1Cxd/Fgfr1tm2.1Cxd | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm2Jrt/Fgfr1tm2Jrt | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm3.1Sor/Fgfr1tm3.1Sor | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm4.1Sor/Fgfr1tm4.1Sor | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm5.2Sor/Fgfr1tm5.2Sor | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm8.1Sor/Fgfr1tm8.1Sor | * | |||||||||||||||||||||||||||||||||||
| Fgfr1tm9.1Sor/Fgfr1tm9.1Sor | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm10.1Sor/Fgfr1tm10.1Sor | ||||||||||||||||||||||||||||||||||||
| Fgfr1Eask/Fgfr1+ | ||||||||||||||||||||||||||||||||||||
| Fgfr1Hspy/Fgfr1+ | ! | |||||||||||||||||||||||||||||||||||
| Fgfr1tm2.1Cxd/Fgfr1+ | ||||||||||||||||||||||||||||||||||||
| Fgfr1tm1Jpa/Fgfr1tm1Jpa H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Fgfr1tm5.1Sor/Fgfr1tm5.1Sor H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Fgfr1tm1Jpa/Fgfr1tm1.1Jpa H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Fgfr1tm5.1Sor/Fgfr1tm9.1Sor H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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| Fgfr1tm5.1Sor/Fgfr1tm10.1Sor H2az2Tg(Wnt1-cre)11Rth/H2az2+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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