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Symbol
Name
ID
Fcgr3
Fc receptor, IgG, low affinity III
MGI:95500
Phenotype annotations related to homeostasis/metabolism
Darker colors indicate more annotations
Human Phenotypes
Increased circulating IgA level
Increased circulating IgE level
Increased circulating IgG level
Decreased circulating antibody level
Paraproteinemia
Reduced erythrocyte adenylate kinase activity
Hypercalcemia
Hyperbilirubinemia
Increased LDL cholesterol concentration
Hypercholesterolemia
Hypertriglyceridemia
Elevated circulating creatinine concentration
Elevated circulating C-reactive protein concentration
Hyperproteinemia
Elevated circulating hepatic transaminase concentration
Reduced circulating pyrimidine 5-prime-nucleotidase activity
Elevated erythrocyte sedimentation rate
Glucose intolerance
Diabetes mellitus
Type II diabetes mellitus
Impaired glucose tolerance
Elevated sweat chloride
Dehydration
Joint swelling
Pleural effusion
Fever
Abnormality of vitamin B12 metabolism
Hypercalciuria
Hematuria
Pyuria
Proteinuria
Hemoglobinuria
Amyloidosis
Disease(s) Associated with FCGR2A
coronary artery disease
cystic fibrosis
factor VIII deficiency
hemolytic anemia
malaria
multiple myeloma
rheumatoid arthritis
systemic lupus erythematosus
temporal arteritis
thrombocytopenia
Disease(s) Associated with FCGR2B
malaria
systemic lupus erythematosus

Mouse Phenotypes
decreased circulating calcium level
decreased circulating creatine kinase level
decreased circulating serum albumin level
decreased circulating total protein level
dehydration
edema
increased urine protein level
Availability Mouse Genotype
Fcgr2btm1Ttk/Fcgr2btm1Ttk
Fcgr3tm1b(EUCOMM)Hmgu/Fcgr3tm1b(EUCOMM)Hmgu

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory