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Symbol
Name
ID
Fbn2
fibrillin 2
MGI:95490
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Arthrogryposis multiplex congenita
Congenital finger flexion contractures
Distal arthrogryposis
Arthrogryposis-like hand anomaly
Camptodactyly
Camptodactyly of finger
Camptodactyly of 2nd-5th fingers
Camptodactyly of toe
Joint contractures involving the joints of the feet
Contractures involving the joints of the feet
Plantar flexion contractures
Hamstring contractures
Hip contracture
Knee flexion contracture
Elbow flexion contracture
Joint contracture of the hand
Wrist flexion contracture
Micrognathia
Mandibular prognathia
Trismus
Microcephaly
Mild microcephaly
Macrocephaly
Frontal bossing
Brachycephaly
Cranial asymmetry
Dolichocephaly
Scaphocephaly
Short neck
Absent phalangeal crease
Absent distal interphalangeal creases
Short phalanx of finger
Adducted thumb
Overlapping fingers
Ulnar deviation of finger
Arachnodactyly
Deviation of the 2nd toe
Fibular deviation of toes
Tibial deviation of toes
Hammertoe
Overlapping toe
Cutaneous syndactyly of toes
Clinodactyly
Cutaneous finger syndactyly
Cutaneous syndactyly between fingers 2 and 5
Aplasia/Hypoplasia of the radius
Tarsal synostosis
Hip dislocation
Congenital hip dislocation
Patellar dislocation
Patellar subluxation
Limited wrist extension
Ulnar deviation of the wrist
Abnormality of the hip bone
Decreased hip abduction
Down-sloping shoulders
Stiff shoulders
Abnormality of the thorax
Abnormality of the rib cage
Pectus carinatum
Pectus excavatum
Vertebral segmentation defect
Hyperlordosis
Lumbar hyperlordosis
Kyphosis
Kyphoscoliosis
Congenital kyphoscoliosis
Scoliosis
Thoracolumbar scoliosis
Lumbar scoliosis
Osteopenia
Joint stiffness
Disease(s) Associated with FBN2
distal arthrogryposis

Mouse Phenotypes
micrognathia
abnormal carpal bone morphology
fused phalanges
abnormal skeleton morphology
decreased bone mass
abnormal joint morphology
abnormal skeleton development
abnormal bone remodeling
Availability Mouse Genotype
Fbn2fp-4J/Fbn2fp-4J
Fbn2mz/Fbn2mz
Fbn2timon/Fbn2timon
Fbn2tm1Rmz/Fbn2tm1Rmz

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/11/2019
MGI 6.14
The Jackson Laboratory