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Symbol Name ID |
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1 MGI:95412 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
| Disease(s) Associated with ERCC1 | ||||
| multiple myeloma |
| Mouse Phenotypes | decreased germ cell number |
abnormal cell nucleus morphology |
abnormal chromosome number |
aneuploidy |
polyploidy |
increased cellular sensitivity to oxidative stress |
abnormal male germ cell apoptosis |
increased retina apoptosis |
increased hepatocyte apoptosis |
decreased B cell proliferation |
decreased cell proliferation |
decreased hepatocyte proliferation |
early cellular replicative senescence |
abnormal DNA repair |
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| Availability | Mouse Genotype | ||||||||||||||
| Ercc1tm1Dwm/Ercc1tm1Dwm | |||||||||||||||
| Ercc1tm1Dwm/Ercc1tm1Dwm Tg(Ttr-Ercc1)17Dwm/0 |
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| Ercc1tm1Jhjh/Ercc1tm1Jhjh | |||||||||||||||
| Ercc1tm2Jhjh/Ercc1tm2Jhjh | |||||||||||||||
| Ercc1tm1Jhjh/Ercc1tm2Jhjh | |||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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