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Symbol Name ID |
Drd2
dopamine receptor D2 MGI:94924 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased resting energy expenditure |
Type II diabetes mellitus |
Insulin resistance |
| Disease(s) Associated with DRD2 | |||
| obesity | |||
| type 2 diabetes mellitus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
decreased response to stress-induced hyperthermia |
increased susceptibility to neuronal excitotoxicity |
increased susceptibility to dopaminergic neuron neurotoxicity |
abnormal circulating hormone level |
decreased circulating estrogen level |
increased circulating corticosterone level |
increased circulating prolactin level |
decreased circulating insulin-like growth factor I level |
decreased circulating growth hormone level |
increased circulating pituitary hormone level |
increased circulating adrenocorticotropin level |
decreased body temperature |
abnormal dopamine level |
increased dopamine level |
abnormal hormone level |
decreased growth hormone level |
increased growth hormone level |
increased pituitary hormone level |
increased urine sodium level |
decreased urine major urinary protein level |
decreased susceptibility to xenobiotic induced morbidity/mortality |
decreased physiological sensitivity to xenobiotic |
increased physiological sensitivity to xenobiotic |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||
| Drd2tm1Ebo/Drd2tm1Ebo | |||||||||||||||||||||||||
| Drd2tm1Low/Drd2tm1Low | |||||||||||||||||||||||||
| Drd2tm1Mok/Drd2tm1Mok | |||||||||||||||||||||||||
| Drd2tm1Schm/Drd2tm1Schm | |||||||||||||||||||||||||
| Drd2tm1Low/Drd2+ | |||||||||||||||||||||||||
| Drd2tm1.1Mrub/Drd2tm1.1Mrub Slc6a3tm1.1(cre)Bkmn/Slc6a3+ (conditional) |
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| Drd2tm1.1Mrub/Drd2tm1.1Mrub Tg(Prl-cre)1Mrub/? (conditional) |
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| Drd2tm1.1Mrub/Drd2tm1.1Mrub Tg(Nes-cre)1Kln/? (conditional) |
* | ||||||||||||||||||||||||
| Drd2tm3.1Ebo/Drd2tm3.1Ebo En1tm2(cre)Wrst/En1+ (conditional) |
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| Drd2tm3.1Ebo/Drd2tm3.1Ebo Tg(Drd1a-cre)AGsc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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