About   Help   FAQ
Symbol
Name
ID
Drd2
dopamine receptor D2
MGI:94924
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Agoraphobia
Anxiety
Depressivity
Obsessive-compulsive behavior
Disease(s) Associated with DRD2
myoclonic dystonia 11

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavior
abnormal behavioral response to xenobiotic
alcohol aversion
decreased alcohol consumption
impaired behavioral response to alcohol
enhanced behavioral response to cocaine
impaired behavioral response to cocaine
impaired behavioral response to addictive substance
enhanced behavioral response to anesthetic
impaired behavioral response to anesthetic
increased susceptibility to pharmacologically induced seizures
enhanced behavioral response to xenobiotic
impaired behavioral response to xenobiotic
impaired conditioned place preference behavior
abnormal latent inhibition of conditioning behavior
abnormal operant conditioning behavior
decreased fluid intake
increased fluid intake
decreased food intake
increased food intake
decreased aggression towards males
decreased anxiety-related response
abnormal response to novel odor
decreased response to stress-induced hyperthermia
decreased startle reflex
ataxia
impaired coordination
hunched posture
limp posture
abnormal locomotor behavior
abnormal locomotor activation
decreased vertical activity
increased vertical activity
akinesia
bradykinesia
hyperactivity
induced hyperactivity
hypoactivity
abnormal gait
unidirectional circling
abnormal social/conspecific interaction
abnormal vocalization
catalepsy
Availability Mouse Genotype
Drd2tm1Ebo/Drd2tm1Ebo *
Drd2tm1Low/Drd2tm1Low *
Drd2tm1Schm/Drd2tm1Schm
Drd2tm1Yyw/Drd2tm1Yyw
Drd2tm2Ebo/Drd2tm2Ebo *
Drd2tm1(IL2RA)Koba/Drd2+
Drd2tm1Ebo/Drd2+
Drd2tm1Low/Drd2+ *
Drd2tm1Yyw/Drd2+
Drd2tm1.1Mmsh/Drd2tm1.1Mmsh
Gng7tm1(cre)Mmsh/?  (conditional)
*
Drd2tm1.1Mrub/Drd2tm1.1Mrub
Slc6a3tm1.1(cre)Bkmn/Slc6a3+  (conditional)
Drd2tm1.1Mrub/Drd2tm1.1Mrub
Tg(Nes-cre)1Kln/?  (conditional)
*
Drd2tm3.1Ebo/Drd2tm3.1Ebo
En1tm2(cre)Wrst/En1+  (conditional)
Drd2tm3.1Ebo/Drd2tm3.1Ebo
Tg(Drd1a-cre)AGsc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory