Symbol
Name
ID

Neurog3
neurogenin 3
MGI:893591

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Type I diabetes mellitus	Type II diabetes mellitus	Insulin resistance	Hyperchloremic metabolic acidosis	Dehydration
Disease(s) Associated with NEUROG3	Type I diabetes mellitus	Type II diabetes mellitus	Insulin resistance	Hyperchloremic metabolic acidosis	Dehydration
congenital malabsorptive diarrhea 4
type 2 diabetes mellitus

Mouse Phenotypes

abnormal intestinal lipid absorption

steatorrhea

increased blood urea nitrogen level

increased circulating bicarbonate level

decreased circulating glucose level

increased circulating glucose level

decreased circulating HDL cholesterol level

decreased circulating cholesterol level

decreased circulating triglyceride level

decreased circulating serum albumin level

dehydration

impaired glucose tolerance

improved glucose tolerance

increased urine glucose level

increased insulin sensitivity

Availability

Mouse Genotype

Neurog3^tm1Fgu/Neurog3^tm1Fgu

Neurog3^{tm1.1(cre/ERT)Ggu}/Neurog3⁺

Neurog3^tm3.1Ggr/Neurog3^tm3.1Ggr
Tg(Vil1-cre)20Syr/0 (conditional)

Neurog3^tm1Fgu/Neurog3^tm3.1Ggr
Tg(Vil1-cre)20Syr/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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