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Symbol Name ID |
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1 MGI:88590 |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Anterior synechiae of the anterior chamber |
Posterior synechiae of the anterior chamber |
Abnormal Descemet membrane morphology |
Thinning of Descemet membrane |
Opacification of the corneal stroma |
Central opacification of the cornea |
Corneal neovascularization |
Corneal opacity |
Subcapsular cataract |
Developmental glaucoma |
Buphthalmos |
Late onset congenital glaucoma |
Peters anomaly |
Ocular hypertension |
Strabismus |
Nystagmus |
Myopia |
Open angle glaucoma |
| Disease(s) Associated with CYP1B1 | ||||||||||||||||||
| anterior segment dysgenesis 6 | ||||||||||||||||||
| buphthalmos | ||||||||||||||||||
| Peters anomaly | ||||||||||||||||||
| primary open angle glaucoma |
| Mouse Phenotypes | abnormal iridocorneal angle |
abnormal canal of Schlemm morphology |
absent Schlemm's canal |
abnormal trabecular meshwork morphology |
hypoplastic trabecular meshwork |
anterior iris synechia |
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| Availability | Mouse Genotype | ||||||
| Cyp1b1tm1Gonz/Cyp1b1tm1Gonz | ! | ||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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