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Symbol
Name
ID
Cyp11b1
cytochrome P450, family 11, subfamily b, polypeptide 1
MGI:88583
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Increased circulating cortisol level
Decreased circulating renin level
Adrenal hyperplasia
Congenital adrenal hyperplasia
Decreased circulating aldosterone level
Hyperaldosteronism
Adrenogenital syndrome
Precocious puberty in males
Premature pubarche
Primary amenorrhea
Disease(s) Associated with CYP11B1
congenital adrenal hyperplasia
glucocorticoid-remediable aldosteronism

Mouse Phenotypes
abnormal adrenal cortex morphology
abnormal adrenal gland zona fasciculata morphology
abnormal adrenal gland zona glomerulosa morphology
abnormal adrenocortical cell morphology
enlarged adrenal glands
adrenal gland hyperplasia
pituitary gland hyperplasia
decreased thymus weight
absent corpus luteum
Availability Mouse Genotype
Cyp11b1tm1Chjk/Cyp11b1tm1Chjk
Cyp11b2tm1Hsk/Cyp11b2tm1Hsk

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory