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Symbol
Name
ID
Ctla4
cytotoxic T-lymphocyte-associated protein 4
MGI:88556
Phenotype annotations related to growth/size/body
Darker colors indicate more annotations
Human Phenotypes
Splenomegaly
Hepatosplenomegaly
Abnormal abdomen morphology
Ascites
Hepatomegaly
Abdominal distention
Tall stature
Failure to thrive
Weight loss
Disease(s) Associated with CTLA4
graft-versus-host disease
granulomatosis with polyangiitis
Graves' disease
multiple myeloma
primary biliary cholangitis
sarcoidosis
systemic lupus erythematosus

Mouse Phenotypes
enlarged heart
enlarged spleen
spleen hyperplasia
Availability Mouse Genotype
Ctla4tm1Shr/Ctla4tm1Shr
Ctla4tm1Saka/Ctla4tm1Saka
Foxp3tm1(cre)Saka/Y  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory