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Symbol
Name
ID
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
MGI:88373
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
abnormal osteoclast differentiation
impaired macrophage phagocytosis
decreased osteoclast cell number
abnormal plasma cell morphology
abnormal osteoclast morphology
abnormal spleen red pulp morphology
enlarged spleen
abnormal spleen white pulp morphology
abnormal spleen secondary B follicle morphology
increased IgG level
abnormal T-helper 1 physiology
abnormal T-helper 2 physiology
abnormal macrophage physiology
abnormal osteoclast physiology
decreased circulating interleukin-10 level
decreased circulating interleukin-12 level
increased circulating interleukin-6 level
increased circulating tumor necrosis factor level
abnormal tumor necrosis factor level
enlarged mesenteric lymph nodes
abnormal lymph node cortex morphology
abnormal lymph node B cell domain morphology
abnormal lymph node secondary follicle morphology
abnormal lymph node T cell domain morphology
abnormal lymph node medulla morphology
abnormal lymph node medullary cord morphology
enlarged lymph nodes
enlarged axillary lymph nodes
enlarged inguinal lymph nodes
enlarged submandibular lymph nodes
abnormal mucosa-associated lymphoid tissue morphology
decreased susceptibility to type IV hypersensitivity reaction
abnormal cell-mediated immunity
abnormal humoral immune response
increased interleukin-12 secretion
decreased susceptibility to endotoxin shock
granulomatous inflammation
myositis
glomerulonephritis
abnormal innate immunity
decreased susceptibility to bacterial infection
decreased susceptibility to bacterial infection induced morbidity/mortality
increased susceptibility to bacterial infection
increased susceptibility to fungal infection
Availability Mouse Genotype
Cebpbtm1.1Acle/Cebpbtm1.1Acle
Cebpbtm1Aki/Cebpbtm1Aki
Cebpbtm1Kish/Cebpbtm1Kish
Cebpbtm1Pfj/Cebpbtm1Pfj
Cebpbtm1Vpo/Cebpbtm1Vpo
Cebpbtm2.1Acle/Cebpbtm2.1Acle
Cebpbtm3Nerl/Cebpbtm3Nerl
Cebpbtm1.1Elgaz/Cebpbtm1.1Elgaz
Lyz2em1.1Elgaz/Lyz2+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory