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Symbol
Name
ID
Cd8b1
CD8 antigen, beta chain 1
MGI:88347
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
decreased thymocyte number
abnormal B cell differentiation
abnormal T cell differentiation
abnormal CD4-positive T cell differentiation
abnormal CD8-positive, alpha-beta T cell differentiation
abnormal double-positive T cell morphology
abnormal T cell subpopulation ratio
increased CD4-positive, alpha beta T cell number
increased central memory CD8 positive, alpha-beta T cell number
increased effector memory CD8-positive, alpha-beta T cell number
decreased CD8-positive, naive alpha-beta T cell number
decreased CD8-positive, alpha-beta T cell number
decreased T cell number
abnormal dendritic cell morphology
abnormal CD8-positive, alpha beta T cell morphology
abnormal gamma-delta intraepithelial T cell morphology
increased IgG level
abnormal cytotoxic T cell physiology
enhanced humoral immune response
Availability Mouse Genotype
Cd8a/Cd8b1tm3Welm/Cd8a/Cd8b1tm3Welm
Cd8b1M1Btlr/Cd8b1M1Btlr
Cd8b1m2Btlr/Cd8b1m2Btlr
Cd8b1tm1Litt/Cd8b1tm1Litt
Cd8b1tm1Wpfl/Cd8b1tm1Wpfl *
Cd8b1M1Btlr/Cd8b1+
Cd8b1tm1Litt/Cd8b1+
Tg(Cd8b1)46Erob/0
Tg(Cd8b1)46Erob/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/14/2020
MGI 6.14
The Jackson Laboratory