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Symbol Name ID |
Cd27
CD27 antigen MGI:88326 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased lymphocyte proliferation in response to mitogen |
Decreased circulating antibody level |
Hemophagocytosis |
Persistent EBV viremia |
Lymphadenopathy |
Hepatosplenomegaly |
Splenomegaly |
Uveitis |
Recurrent pneumonia |
Sepsis |
Recurrent infections |
Severe varicella zoster infection |
| Disease(s) Associated with CD27 | ||||||||||||
| lymphoproliferative syndrome 2 |
| Mouse Phenotypes | immune system phenotype |
increased T cell apoptosis |
abnormal leukopoiesis |
decreased regulatory T cell number |
increased leukocyte cell number |
abnormal T cell physiology |
abnormal CD4-positive, alpha-beta T cell physiology |
abnormal cytotoxic T cell physiology |
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| Availability | Mouse Genotype | ||||||||
| Cd27tm1Jbo/Cd27tm1Jbo | * | ||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO) |
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last database update 02/23/2021 MGI 6.16 |
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