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Symbol
Name
ID
Cd27
CD27 antigen
MGI:88326
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Decreased lymphocyte proliferation in response to mitogen
Decreased circulating antibody level
Hemophagocytosis
Persistent EBV viremia
Lymphadenopathy
Hepatosplenomegaly
Splenomegaly
Uveitis
Recurrent pneumonia
Sepsis
Recurrent infections
Severe varicella zoster infection
Disease(s) Associated with CD27
lymphoproliferative syndrome 2

Mouse Phenotypes
immune system phenotype
increased T cell apoptosis
abnormal leukopoiesis
decreased regulatory T cell number
increased leukocyte cell number
abnormal T cell physiology
abnormal CD4-positive, alpha-beta T cell physiology
abnormal cytotoxic T cell physiology
Availability Mouse Genotype
Cd27tm1Jbo/Cd27tm1Jbo *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory