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Symbol
Name
ID
Ctnnb1
catenin (cadherin associated protein), beta 1
MGI:88276
Phenotype annotations related to reproductive system
Darker colors indicate more annotations
Human Phenotypes
Dysgerminoma
Ovarian papillary adenocarcinoma
Endometrial carcinoma
Uterine leiomyosarcoma
Disease(s) Associated with CTNNB1
colorectal cancer
ovarian cancer

Mouse Phenotypes
abnormal spermatogonia morphology
squamous metaplasia of preputial gland
squamous metaplasia of bulbourethral gland
abnormal seminiferous tubule morphology
seminiferous tubule degeneration
decreased testis weight
testicular atrophy
increased ovary tumor incidence
increased granulosa cell tumor incidence
increased prostate gland adenocarcinoma incidence
increased prostate intraepithelial neoplasia incidence
increased testis tumor incidence
abnormal foreskin morphology
abnormal external female genitalia morphology
abnormal external male genitalia morphology
abnormal sex determination
male infertility
Availability Mouse Genotype
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Gli1tm3(cre/ERT2)Alj/Gli1+  (conditional)
Ctnnb1tm1Mmt/Ctnnb1tm1Mmt
Nanos3tm2(cre)Ysa/Nanos3+  (conditional)
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Emx1tm1(cre)Yql/Emx1+  (conditional)
Ctnnb1tm2Kem/Ctnnb1tm2Kem
Nanos3tm2(cre)Ysa/Nanos3+  (conditional)
Ctnnb1tm4Wbm/Ctnnb1tm4Wbm
Gli1tm3(cre/ERT2)Alj/Gli1+  (conditional)
Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm2Kem/Ctnnb1tm2.1Kem  (conditional)
Amhr2tm3(cre)Bhr/Amhr2+
Ctnnb1tm1Mmt/Ctnnb1+  (conditional)
Ctnnb1tm1Mmt/Ctnnb1+
Tg(Pbsn-cre)4Prb/0  (conditional)
Ctnnb1tm1Mmt/Ctnnb1+
Tg(CYP19A1-cre)1Jri/0  (conditional)
Ctnnb1tm1Mmt/Ctnnb1+
Nanos3tm2(cre)Ysa/Nanos3+  (conditional)
Ctnnb1tm2Kem/Ctnnb1+
Nanos3tm2(cre)Ysa/Nanos3+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory