|
Symbol Name ID |
Ctnnb1
catenin beta 1 MGI:88276 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Breast carcinoma |
Hereditary nonpolyposis colorectal carcinoma |
Adenomatous colonic polyposis |
Neoplasm of the stomach |
Hepatocellular carcinoma |
Dysgerminoma |
Ovarian papillary adenocarcinoma |
Uterine leiomyosarcoma |
Nephroblastoma |
Renal cell carcinoma |
Transitional cell carcinoma of the bladder |
Pilomatrixoma |
Spinal cord tumor |
Medulloblastoma |
Cerebellar medulloblastoma |
Neuroblastoma |
Neoplasm of the lung |
| Disease(s) Associated with CTNNB1 | |||||||||||||||||
| colorectal cancer | |||||||||||||||||
| hepatocellular carcinoma | |||||||||||||||||
| medulloblastoma | |||||||||||||||||
| nephroblastoma | |||||||||||||||||
| ovarian cancer | |||||||||||||||||
| pilomatrixoma |
| Mouse Phenotypes | neoplasm |
increased intestinal adenoma incidence |
increased mammary gland tumor incidence in breeding females |
increased ovary tumor incidence |
increased granulosa cell tumor incidence |
increased pituitary gland tumor incidence |
increased prostate gland adenocarcinoma incidence |
increased prostate intraepithelial neoplasia incidence |
increased testis tumor incidence |
increased incidence of tumors by chemical induction |
increased hepatoblastoma incidence |
increased urinary bladder carcinoma incidence |
increased osteoma incidence |
increased tumor incidence |
|
| Availability | Mouse Genotype | ||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ | |||||||||||||||
| Ctnnb1tm1.1Smoc/Ctnnb1tm1.1Smoc Sox9em1(cre/ERT2)Tchn/Sox9+ (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1tm1Mmt Tg(Mx1-cre)1Cgn/0 (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1tm1Mmt Tg(Upk2-cre)6Xrw/0 (conditional) |
* | ||||||||||||||
| Ctnnb1tm2Kem/Ctnnb1tm2Kem Tcf21tm1(cre)Seq/Tcf21+ (conditional) |
|||||||||||||||
| Amhr2tm3(cre)Bhr/Amhr2+ Ctnnb1tm1Mmt/Ctnnb1+ (conditional) |
|||||||||||||||
| Bmi1tm1(cre/ERT)Mrc/Bmi1+ Ctnnb1tm1Mmt/Ctnnb1+ (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Krt19tm1(cre)Mmt/Krt19+ (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Fabp1-cre)1Mmt/? (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Mx1-cre)1Cgn/0 (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Pbsn-cre)4Prb/0 (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Upk2-cre)6Xrw/0 (conditional) |
* | ||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Col1a1-cre)1Kry/0 (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Tg(CYP19A1-cre)1Jri/0 (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Dclk1tm1.1(cre/ERT2)Seno/Dclk1+ (conditional) |
* | ||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Krt14tm1.1(cre)Wbm/Krt14+ (conditional) |
* | ||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Sox2tm1.1(cre/ERT2)Jpmb/Sox2+ (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Msx2-rtTA)885Lma/0 Tg(tetO-cre)1Jaw/0 (conditional) |
|||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Wap-cre)11738Mam/0 (conditional) |
|||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/09/2024 MGI 6.23 |
|
|
|
||
Analysis Tools