Symbol
Name
ID

Bmp2
bone morphogenetic protein 2
MGI:88177

Phenotype annotations related to limbs/digits/tail

Darker colors indicate more annotations

Human Phenotypes

Aplasia/Hypoplasia of the middle phalanx of the 2nd finger

Triangular shaped middle phalanx of the 2nd finger

Short 2nd finger

Radial deviation of the 2nd finger

Ulnar deviation of the 2nd finger

Aplasia/Hypoplasia of the middle phalanx of the 5th finger

Short middle phalanx of the 5th finger

Triangular shaped middle phalanx of the 5th finger

Clinodactyly of the 5th finger

Short middle phalanx of finger

Short hallux

Broad hallux

Hallux valgus

Medially deviated second toe

2-3 toe syndactyly

Type A2 brachydactyly

Short foot

Short 2nd metacarpal

Abnormal metacarpophalangeal joint morphology

Palmoplantar hyperhidrosis

Palmar hyperkeratosis

Disease(s) Associated with BMP2

brachydactyly type A2

hemochromatosis type 1

tooth agenesis

Mouse Phenotypes		syndactyly	absent deltoid tuberosity	short humerus	kinked tail
Availability	Mouse Genotype	syndactyly	absent deltoid tuberosity	short humerus	kinked tail
	Bmp2^tm1Brd/Bmp2^tm1Mis
	Bmp2^tm1Cjt/Bmp2^tm1Cjt Tg(Prrx1-cre)1Cjt/0 (conditional)
	Bmp2^tm1.1Mis/Bmp2^tm1.2Mis Tg(Col1a1-cre)1Bek/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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