Symbol Name ID |
Apoe
apolipoprotein E MGI:88057 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Neurofibrillary tangles |
Long-tract signs |
Alzheimer disease |
Senile plaques |
Parkinsonism |
Apraxia |
Cognitive impairment |
Memory impairment |
Dementia |
Sleep-wake cycle disturbance |
Parietal hypometabolism in FDG PET |
Disease(s) Associated with APOE | |||||||||||
Alzheimer's disease 2 | |||||||||||
Alzheimer's disease 4 |
Mouse Phenotypes | nervous system phenotype |
abnormal kindling response |
abnormal blood-brain barrier function |
hypopituitarism |
cochlear inner hair cell degeneration |
cochlear outer hair cell degeneration |
abnormal response to CNS ischemic injury |
decreased cerebral infarction size |
abnormal hippocampus morphology |
abnormal cerebral cortex morphology |
abnormal neuron morphology |
abnormal myelin sheath morphology |
abnormal dendrite morphology |
abnormal synapse morphology |
abnormal synaptic vesicle morphology |
cochlear ganglion degeneration |
abnormal sciatic nerve morphology |
abnormal astrocyte physiology |
|
Availability | Mouse Genotype | ||||||||||||||||||
Apoetm1Bres/Apoetm1Bres | |||||||||||||||||||
Apoetm1Unc/Apoetm1Unc | * | ||||||||||||||||||
Apoetm2(APOE_i2)Sfu/Apoetm2(APOE_i2)Sfu |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO) |
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last database update 02/16/2021 MGI 6.16 |
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