Symbol Name ID |
Apoc3
apolipoprotein C-III MGI:88055 |
Darker colors indicate more annotations |
Human Phenotypes | Decreased level of 1,5 anhydroglucitol in serum |
Increased HDL cholesterol concentration |
Decreased LDL cholesterol concentration |
Increased LDL cholesterol concentration |
Increased VLDL cholesterol concentration |
Hypercholesterolemia |
Hyperlipidemia |
Hypertriglyceridemia |
Hypotriglyceridemia |
Elevated circulating apolipoprotein A-II concentration |
Elevated circulating apolipoprotein B concentration |
Hyperglycemia |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Ketoacidosis |
Disease(s) Associated with APOC3 | |||||||||||||||||
apolipoprotein C-III deficiency | |||||||||||||||||
coronary artery disease | |||||||||||||||||
familial combined hyperlipidemia | |||||||||||||||||
type 1 diabetes mellitus |
Mouse Phenotypes | increased susceptibility to diet-induced obesity |
abnormal blood homeostasis |
increased circulating glucose level |
increased circulating leptin level |
increased circulating ketone body level |
decreased circulating HDL cholesterol level |
decreased circulating LDL cholesterol level |
decreased circulating VLDL cholesterol level |
decreased circulating cholesterol level |
decreased circulating triglyceride level |
decreased energy expenditure |
insulin resistance |
abnormal lipid homeostasis |
lipidosis |
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Availability | Mouse Genotype | ||||||||||||||
Apoc3tm1Unc/Apoc3tm1Unc | |||||||||||||||
Apoc3tm1Unc/Apoc3+ |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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