About Help FAQ

Symbol
Name
ID

Apc
APC, WNT signaling pathway regulator
MGI:88039

Phenotype annotations related to craniofacial

Darker colors indicate more annotations

Human Phenotypes	Progressive macrocephaly	Delayed cranial suture closure	Supernumerary tooth	Eruption failure	Carious teeth	Odontoma
Disease(s) Associated with APC	Progressive macrocephaly	Delayed cranial suture closure	Supernumerary tooth	Eruption failure	Carious teeth	Odontoma
familial adenomatous polyposis 1
medulloblastoma

Mouse Phenotypes

abnormal craniofacial morphology

abnormal cranium morphology

absent upper incisors

abnormal tooth development

absent teeth

abnormal mandible morphology

absent mandible

acrania

increased forehead pigmentation

abnormal ear shape

increased ear pigmentation

Availability

Mouse Genotype

Apc^Min/Apc^tm1Tno

Apc^tm1.1Tno/Apc^tm1Tno

Apc^tm1Rsmi/Apc^tm1Rsmi
Tg(Col2a1-cre)1Rsjo/0 (conditional)

Apc^tm2Rak/Apc^tm2Rak
Tg(KRT14-cre)8Brn/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23