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Symbol
Name
ID
Akt1
thymoma viral proto-oncogene 1
MGI:87986
Phenotype annotations related to neoplasm
Darker colors indicate more annotations
Human Phenotypes
Lipoma
Multiple lipomas
Breast carcinoma
Lymphangioma
Hemangioma
Colorectal polyposis
Hereditary nonpolyposis colorectal carcinoma
Colon cancer
Neoplasm of the stomach
Dysgerminoma
Ovarian papillary adenocarcinoma
Endometrial carcinoma
Uterine leiomyosarcoma
Renal cell carcinoma
Transitional cell carcinoma of the bladder
Carcinoma
Disease(s) Associated with AKT1
breast cancer
colorectal cancer
ovarian cancer
Proteus syndrome

Mouse Phenotypes
increased trichoepithelioma incidence
abnormal tumor morphology
increased carcinoma incidence
increased adenocarcinoma incidence
increased squamous cell carcinoma incidence
Availability Mouse Genotype
Tg(KRT5-Akt1*)Jmpa/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory