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Symbol
Name
ID
Agtr1a
angiotensin II receptor, type 1a
MGI:87964
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hypercalcemia
Increased LDL cholesterol concentration
Hypercholesterolemia
Hypertriglyceridemia
Increased CSF protein concentration
Glucose intolerance
Diabetes mellitus
Type II diabetes mellitus
Impaired glucose tolerance
Joint swelling
Pleural effusion
Chylothorax
Fever
Hypothermia
Hypercalciuria
Scarring
Disease(s) Associated with AGTR1
coronary artery disease
sarcoidosis

Mouse Phenotypes
homeostasis/metabolism phenotype
decreased urine creatinine level
abnormal blood homeostasis
increased blood urea nitrogen level
decreased circulating angiotensin II level
decreased circulating renin level
increased circulating renin level
abnormal renal water reabsorption
decreased urine potassium level
increased urine osmolality
increased renin activity
abnormal response/metabolism to endogenous compounds
abnormal physiological response to xenobiotic
decreased physiological sensitivity to xenobiotic
decreased susceptibility to injury
Availability Mouse Genotype
Agtr1atm1Afu/Agtr1atm1Afu
Agtr1atm1Ecl/Agtr1atm1Ecl
Agtr1atm1Unc/Agtr1atm1Unc
Agtr1atm1Afu/Agtr1a+ *
Agtr1atm1.1Cof/Agtr1atm1.1Cof
Hprt1tm1(Pck1-cre)Vhh/Hprt1+  (conditional)
Agtr1atm1.1Uky/Agtr1atm1.1Uky
Tg(Fabp4-cre)1Rev/0  (conditional)
*
Agtr1atm3Tma/Agtr1atm3Tma
Tg(Nphs1-cre)10Mska/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory