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Symbol
Name
ID
Agt
angiotensinogen
MGI:87963
Phenotype annotations related to homeostasis/metabolism
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Elevated circulating creatinine concentration
Elevated circulating hepatic transaminase concentration
Decreased alpha-galactosidase A activity
Decreased resting energy expenditure
Type I diabetes mellitus
Edema
Lymphedema
Pulmonary edema
Elevated circulating globotriaosylceramide concentration
Urinary mulberry cells
Proteinuria
Lipiduria
Disease(s) Associated with AGT
Fabry disease
obesity
pre-eclampsia

Mouse Phenotypes
homeostasis/metabolism phenotype
increased circulating creatinine level
abnormal blood homeostasis
increased circulating antidiuretic hormone level
decreased circulating aldosterone level
decreased circulating angiotensinogen level
increased circulating renin level
abnormal enzyme/coenzyme level
decreased urine aldosterone level
increased urine antidiuretic hormone level
decreased urine potassium level
decreased urine sodium level
decreased urine osmolality
Availability Mouse Genotype
Agttm1Afu/Agttm1Afu
Agttm1Ii/Agttm1Ii
Agttm1Unc/Agttm1Unc
Agttm1Afu/Agt+
Agttm1Unc/Agt+
Agttm1.1Itl/Agttm1.1Itl
Tg(Fabp4-cre)1Rev/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory