Symbol
Name
ID

Adamts17
ADAM metallopeptidase with thrombospondin type 1 motif 17
MGI:3588195

Phenotype annotations related to skeleton

Darker colors indicate more annotations

Human Phenotypes

Brachycephaly

Broad skull

Hypoplasia of the maxilla

Shallow orbits

Broad phalanges of the hand

Short thumb

Short finger

Flexion contracture of toe

Brachydactyly

Short metatarsal

Broad metatarsal

Short metacarpal

Broad metacarpals

Elbow flexion contracture

Limitation of joint mobility

Joint stiffness

Delayed skeletal maturation

Broad ribs

Lumbar hyperlordosis

Scoliosis

Spinal canal stenosis

Thin bony cortex

Disease(s) Associated with ADAMTS17

Weill-Marchesani syndrome

Mouse Phenotypes		decreased cranium height	brachyphalangia	short humerus	short tibia	short metacarpal bones	decreased width of hypertrophic chondrocyte zone	decreased length of long bones	abnormal vertebrae morphology	delayed chondrocyte differentiation	abnormal skeleton development
Availability	Mouse Genotype	decreased cranium height	brachyphalangia	short humerus	short tibia	short metacarpal bones	decreased width of hypertrophic chondrocyte zone	decreased length of long bones	abnormal vertebrae morphology	delayed chondrocyte differentiation	abnormal skeleton development
	Adamts17^tm1.2Taks/Adamts17^tm1.2Taks
	Adamts17^tm1.1Taks/Adamts17^tm1.1Taks Tg(Col2a1-cre)1Bhr/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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