About   Help   FAQ
Symbol
Name
ID
Nlrc4
NLR family, CARD domain containing 4
MGI:3036243
Phenotype annotations related to immune system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
immune system phenotype
enlarged spleen
increased neutrophil cell number
increased T cell number
abnormal spleen morphology
increased splenocyte number
abnormal macrophage physiology
increased circulating interleukin-1 beta level
increased circulating interleukin-17 level
abnormal cytokine secretion
decreased interleukin-1 beta secretion
increased interleukin-1 beta secretion
decreased inflammatory response
increased inflammatory response
joint inflammation
arthritis
skin inflammation
dermatitis
abnormal response to infection
increased susceptibility to bacterial infection
increased susceptibility to bacterial infection induced morbidity/mortality
Availability Mouse Genotype
Nlrc4em1Vnce/Nlrc4em1Vnce
Nlrc4em2Vnce/Nlrc4em2Vnce
Nlrc4em3Vnce/Nlrc4em3Vnce *
Nlrc4m1Btlr/Nlrc4m1Btlr
Nlrc4tm1Gln/Nlrc4tm1Gln *
Nlrc4tm1Gne/Nlrc4tm1Gne *
Nlrc4tm1Nnz/Nlrc4tm1Nnz
Nlrc4tm1Vmd/Nlrc4tm1Vmd
Nlrc4m1Btlr/Nlrc4+
Tg(Cd74-Nlrc4*)1Kyas/0

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory