|
Symbol Name ID |
Pdp1
pyruvate dehydrogenase phosphatase catalytic subunit 1 MGI:2685870 |
| Darker colors indicate more annotations |
| Human Phenotypes | Decreased activity of the pyruvate dehydrogenase complex |
Increased serum pyruvate |
Hyperalaninemia |
Hyperammonemia |
Abnormal CSF pyruvate family amino acid concentration |
Increased CSF lactate |
Decreased resting energy expenditure |
Chronic lactic acidosis |
Increased circulating lactate concentration |
Lactic acidosis |
Congenital lactic acidosis |
Severe lactic acidosis |
Metabolic acidosis |
| Disease(s) Associated with PDP1 | |||||||||||||
| obesity | |||||||||||||
| pyruvate decarboxylase deficiency |
| Mouse Phenotypes | increased fasting circulating glucose level |
improved glucose tolerance |
|
| Availability | Mouse Genotype | ||
| Pdp1em1(IMPC)Mbp/Pdp1em1(IMPC)Mbp | |||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/09/2024 MGI 6.23 |
|
|
|
||
Analysis Tools